The main focus of Prof Hamilton’s current research is the control of the development of cells of the monocyte/macrophage lineage and the function of this lineage in inflammatory disease and pain.

Prof Hamilton’s work has specific relevance to arthritic disease and pain in particular, but also has wide implication for many aspects of inflammation and pathology and therefore many diseases.

Several potential targets for drug intervention and four recent Phase II trials in rheumatoid arthritis have arisen from his work.