The Endocrinology & Diabetes Unit at Western Health provides a broad clinical service covering type 1 and type 2 diabetes, diabetic foot, insulin pumps, endocrinology, obstetric endocrinology and metabolic bone. Clinical research areas focus on diabetes, metabolic bone disease and obstetric endocrinology.
Diabetes research projects include: the psychosocial factors involved in diabetic ketoacidosis; the impact of glucocorticoids (‘steroids’) on blood glucose control in obstetric and oncology patients; diabetic foot studies; Chronic disease IMPACT study (Western Health Chronic Disease Alliance) which uses software to identify cardiovascular risks (including diabetes) in general practice and helps GPs manage patients with established disease; Type 1 diabetes data registry development (Australian Diabetes Data Network: ADDN2) which facilitates type 1 diabetes research nationally in adults with type 1 diabetes.
Metabolic bone studies include the effect of parathyroidectomy on a number of outcomes in Western Health patients who have a variety of ethnic backgrounds and often low Vitamin D levels; collaborative research with Prof Duque on the effects of parathyroidectomy in frail older persons (Frail-pathy study); obstetric endocrinology: studies of trimester-specific normal thyroid function reference intervals in the Western Health population.

A/Prof Shane Hamblin (Head Endocrinology & Diabetes Unit)
Program Director
Shane Hamblin is studying the psychosocial factors associated with the high rates of diabetic ketoacidosis at Western Health. He is also collaborating with the Australian Diabetes Data Network for type 1 diabetes research sponsored by JDRF and is involved in an investigator initiated pharmaceutical trial of a novel agent to improve diabetic nephropathy.
We are working on common endocrine diseases affecting patients from the Western Health catchment: diabetes (type 1, type 2 and gestational diabetes) and hyperparathyroidism. We are in addition developing studies on clinical aspects of osteoporosis in younger people and also the consequences of androgen deprivation therapy in men treated for prostate cancer. Another theme relates to evaluation of thyroid function tests in pregnancy.
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